of course

,of `course adverb ***

1. ) used for saying yes very definitely, in answer to a question:

Do you know what I mean? Of course.

a ) used for giving someone permission in a polite way:

May I come in? Of course you may.

b ) used for agreeing or disagreeing with someone:

I'm sure everything's going to be OK. Of course it is.

They won't mind if we're a bit late. Of course they will.

2. ) used for saying something that you think someone probably already knows or will not be surprised about:

I will, of course, make sure you're all kept fully informed.

He found out in the end, of course.

3. ) used when you have just realized something:

Of course! That's why she didn't want to come.

of course not

1. ) used for saying no very definitely in answer to a question:

Aren't you afraid of what people will say? Of course not.

2. ) used for refusing to give someone permission:

Can I borrow the car again tonight? Of course not. You know I need it.

3. ) used for agreeing or disagreeing with someone:

I don't think anyone else should be told about this. Of course not.

I know you all want me to leave. Of course not.